Leading experts explore the pragmatic application of the tools of genomic and molecular biology research to the treatment of stroke. The authors relate changes in gene expression to physiological endpoints-such as functional imaging paradigms-to produce a more holistic approach in which molecular biology goes hand-in-hand with stroke pathophysiology. The book shows how to successfully design, execute, and interpret preclinical and clinical molecular biological studies of stroke as well as rapid development of the next generation of stroke therapeutics.
From the reviews:
"The protocols presented in Stroke Genomics: Methods and Reviews will greatly benefit scientists interested in the molecular biology as well as the genetic and genomic basis of strokes." - Journal of Chemical Neuroanatomy
"...very interesting and informative...an attractive and interesting overview of the different aspects of the current stroke research...can be recommended as a source of useful and up-to-date practical and theoretical information on stroke genetics and on stroke associated gene expression." - European Neurology
"This book gives the opportunity for experts in the field to explore the practical and experimental applications of genomic and molecular biology research to the treatment of stroke. ? The book also indicates detailed methods for studying the molecular biology of stroke. ? It can be recommended if one is interested in the basic scientific background that underlies central nervous system pathology ? ." (J. V. Byrne, Neuroradiology, Vol. 47, 2005)
