In Rogue Cells, Oober Mann emerges from his cryobed on high alert in New Haudenosaunee, a nation at war with the mysterious territory Nutella during a critical election year. Citizens here live in dread of celebrities who carry out terrorist actions in defence of their own fundamentalist belief systems, including Stratford-upon-Avonists, whose guerrilla conflicts stem from slight variations of Shakespearian texts; Drumhellerists, whose discovery of some dinosaur bones results in a polygamous sect; and Chaos!tologists whose divine teachings are to be found in an obscure book with questionable authorship. Mixed up in an assassination plot being investigated by ISM (Insurgent Saddo Management) and DNA-specialist cops, Mann begins to wonder about the nature of reality and even about the new woman in his life, a femme fatale known only as the Librarian.

It is the Age of Aquarium in the speculative "green" dystopia of Carbon Harbour. Omni-magnate Cornelius Quartz is overseeing the merger between Bildung Endustries and Foreign Objects, but is distracted by an imminent double wedding for himself and his daughter; by the loss of his best promoter and lover to his rival, Zirconium Bluff; and by working conditions in the rehashing core and on wind pharms for hardlucks who harvest bio-material to produce architecture, clothing, and other swag for a luxury class of hardcore gamers (they pay for "pollution fantasies" with carbon credits on extended getaways to Putridworld). Threats to these halcyon days include a new religion publicized by Minor and his daughter Diminuenda that is "Old Testament-style," Mr. Goo's long-awaited release of the "MeMeMe" device, an interstellar pipeline project, the proliferation of aquacukes and giant composting worms that are rapidly running out of garbage, a word virus cultivated by the last carbon-based poet, and the controversial awarding of the Ignoble Prize. Rogue Cells / Carbon Harbour resumes The Chaos! Quincunx novel series.