An exploration of the main questions of signaling mechanisms of reactive oxygen and nitrogen species in enzymatic processes. It covers free radical signaling processes catalyzed by enzymes - producers of superoxide and nitric oxide that are able to use produced ROS and RNS as signaling species in their own catalytic processes.
Once the existence of free radicals was proven, an avalanche of studies on free radical-mediated biological processes ensued. The study of reactive oxygen and nitrogen species (ROS and RNS) is center stage in biological free radical investigations. Written by a biochemist, Signaling Mechanisms of Oxygen and Nitrogen Free Radicals discusses the regulatory functions of ROS and RNS in physiological and pathophysiological states.