Scholars working among an array of "technologies" and "Americas" were invited to contribute to this special bound issue of American Quarterly to interrogate why one might study technology in a post-Eurocentric, post-national American Studies. This volume offers a re-reading of the narrative of U.S. technologies as we move beyond celebrations of exceptional tinkerers and a deterministic machine-driven sense of progress to a more complex understanding of the opportunities and responsibilities that befall a nation that interweaves its identities, labors, and creative cultures with its machines. This volume puts a variety of conversations in dialogue, including the present and historical, the national and international, the material and theoretical, and the critical and celebratory.