Platelet rich fibrin (PRF) is an autogenous biomaterial consisting of growth factors and cytokines entrapped in a fibrin matrix. It combines the fibrant sealant properties along with growth factors thereby providing an ideal environment for wound healing and regeneration of tissues. It can be obtained from blood with the help of a simple process. PRF is basically a concentrate of growth factors that promote wound healing and regeneration which is used in various disciplines of dentistry to repair various lesions and regenerate dental and oral tissues. In recent times it has been used various disciplines in dentistry in a wide range of treatment modalities.