Newly updated to reflect the latest research and medical guidance, the 2020-21 Guide to Medications for the Treatment of Diabetes offers a bridge between drug handbooks and pharmacology texts.
Focusing entirely on diabetes drugs, this reference is divided into two sections:
- Drugs used to manage hyperglycemia, and
- Management of diabetic comorbidities.
The first section includes:
- Pharmacologic Therapy for Type 1 Diabetes
- Management of Hyperglycemia in Type 1 DM– info from practical use of insulin, pathophysiology, treatment strategy
- Insulins: RAIAs, Short-acting insulins, intermediate-acting insulins, LAIAs, Concentrated Insulins, Insulin pumps and patches, inhaled insulins, mixed and mixing insulin, use in Type 1, use in Type 2
- Pharmacologic Therapy for Type 2 Diabetes
- Management of Hyperglycemia in Type 2- brief overview, pathophysiology, treatment strategy, overview of medications
- Biguanides
- TZDs
- SUs
- Glinides
- SGLT-2 Inhibitors
- AGIs
- DPP-IV inhibitors
- GLP Ras
- Amylin mimetics
- BARs
- DA-2 agonists
Each chapter in Section 1 includes:
- Drug class overview and role in diabetes treatment
- Pharmacology: a. Mechanism of action, b. Pharmacokinetics
- Treatment Advantages/Disadvantages: General for the class, b. When applicable, a discussion of evidence that supports the benefits of using a particular drug in a class over another in the same class (eg, Avandia vs Actos)
- Therapeutic Considerations: a. Significant Warnings/Precautions, b. Special Populations, c. Pharmacogenomics, d. Adverse effects and monitoring, e. Drug Interactions, f. Dosage and administration
- Table with Doses and Dose Adjustments
- List of important combination products
- References
The second section includes:
- Cardiovascular Disease and Risk Management
- Microvascular Complications and Foot Care
- Medications for the Management of Hypertension
- Medications for the Management of Hyperlipidemia
- Antiplatelet Therapy
- Medications for Smoking Cessation
- Medications for the Management of Neuropathy (peripheral and autonomic)
- Medications for the Management of Nephropathy
- Medications for the Management of Retinopathy
- Medications for the Management of Depression
- Medications for the Management of Hypoglycemia
- Medications for the Management of Obesity
- Immunizations in Patients with Diabetes
Each chapter in Section 2 includes:
- An overview of the condition or problem
- Goals of treatment
- Overview of the medications and rationale for the medications used for the problem
- Overview of each class of medication
- Overview of combination therapy: a. first combination, b. second combination
- Doses and Dose Adjustments for the more salient medications
- List of important combination products
- References
The 2020-2021 Guide to Medications for the Treatment of Diabetes Mellitus is a complete reference for every physician, clinician, and educator treating people with diabetes. Compiled and edited by a team of noted pharmacology experts specializing in diabetes care, this guide covers all aspects of diabetes drug classes including insulins, biguanides, thiazolidinediones, sulfonylureas, glinides, SGLT2 inhibitors, a-glucosidase inhibitors, DPP-4 inhibitors, GLP-1 RAs, pramlintide, bile acid sequestrants, and dopamine-2 RAs. Chapters cover the management of hyperglycemia in type 1 diabetes and an overview of medications used to treat type 2 diabetes.
This guide also includes chapters on medications to manage comorbidities such as:
- Neuropathy
- Nephropathy
- Retinopathy
- Depression
- Hypoglycemia
- Obesity
