This is the first volume, of two, of the Proceedings of the 38th eCAADe, held as an online event, from 16-17 September 2020 at the Institute of Architecture, Technische Universität Berlin, in Germany. The two volumes together contain the 144 accepted papers. All papers are also available digitally at CumInCAD (Cumulative Index of Computer Aided Architectural Design) ¿ http://papers.cumincad.org Humans and technology today form an inseparable link that has profound implications for Earth¿s ecosystems ¿ leading to the debate for a new era: the Anthropologic. In recent years, the transition from analog to digital architecture has materialized through increasing availability of novel software and new methods in digital architecture fabrication ¿ tooling. The cognitive and digital turn implies ubiquitous computing, artificial intelligence, augmented reality and material intelligence, but to mention a few. The resulting design strategies overwhelm our discipline of architecture, encouraging a re-thinking of architecture, the architect¿s role and responsibility, as well as architectural education. The development of digital technologies is compounding the need to develop ethics for this new technological state ¿ shifting computer architecture from its focus on technology to a focus on humans.