The purpose of the study was to examine the relationship between working conditions and teachers attrition. The specific objectives of the study were, to examine the relationship between; teachers' salaries and teachers' attrition, working environment and teachers' attrition, job satisfaction and teachers' attrition, principals' leadership styles and teachers' attrition, and to determine the impact of teachers' attrition on the quality of education. The cross sectional survey research design was used for this study, adopting both the quantitative and qualitative approaches. The population of the study was made up of all the secondary school teachers in the South West Region. The sample population was made up of 370 teachers. The Simple random sampling technique was used. Questionnaire and an interview guide were used as instruments for data collection. The statistical tools for analysis were percentages, mean scores, standard deviations and the Pearson Product Moment Correlation Coefficient. The findings revealed that, low salary, poor working environment, lack of job satisfaction and bad principal leadership style contribute greatly to teacher attrition.