This book introduces and reviews the essential principles of Veterinary Public Health, Zoonoses, One Health, principles and applications of epidemiology in studying infectious diseases including foodborne infections and intoxications. The initial chapters discuss the concept and principal functions of Veterinary Public Health. The book further covers the impacts of Veterinary Public Health on human Health particularly in management of zoonoses. The following section discusses theapplication of epidemiology in the study of outbreaks, epidemic, pandemics and their prevention and control strategies. It helps understanding the factors associated with disease causation transmission and spread and also investigate the emergence of antimicrobial resistance. The chapter on foodborne illnesses illustrates how the knowledge of epidemiology is applied in the study of diseases in community, spread of causative agents from farm to fork. The definition, cause, symptoms, management, control and prevention of foodborne infection and intoxication are dealt with. The last chapter introduces the concept, objectives, and definition of One Health and discusses the advancements made and challenges in One Health around endemic and emerging zoonotic diseases.