This is the third and final volume of North Atlantic Books’ hard cover edition of Dale Pendell's Pharmako trilogy, an encyclopedic study of the history and uses of psychoactive plants and related synthetics first published between 1995 and 2005. The books form an interrelated suite of works that provide the reader with a unique, reliable, and often personal immersion in this medically, culturally, and spiritually fascinating subject. All three books are beautifully designed and illustrated, and are written with unparalleled authority, erudition, playfulness, and range.

Pharmako/Gnosis: Plant Teachers and the Poison Path focuses on plant-based and derivative psychedelic "teachers" (including ayahuasca, peyote, LSD, and DMT) and on the "poison path" of substances such as belladonna, ketamine, and ibogaine. Each substance is explored in detail, not only with information on its history, pharmacology, preparation, and cultural and esoteric correspondences, but also the subtleties of each plant's effect on consciousness in a way that only poets can do. The whole concoction is sprinkled with abundant quotations from famous writers, creating a literary brew as intoxicating as its subject.

The Pharmako series includes the predecessor volumes Pharmako/Poeia (which covers tobacco, alcohol, cannabis, opiates, salvia divinorum, and other substances) and Pharmako/Dynamis (focusing on stimulants and empathogens). "Essential reading, a modern classic."
—Stephen Silberman, Wired Magazine

"The poet of plantsÉPendel may be America’s answer to Blake, Coleridge and Wordsworth…."
—Emily Green, Los Angeles Times

"Whereas all other drug encyclopaediaists are accompanied by excessive slyness, the seemingly free verse of Dale Pendell is constrained by compulsive accuracy, to paraphrase Zarathustra's Hom Yost, by the (scruples) that drive forth truth."
—David Flattery, author of Haoma and Harmaline

"A beat alchemist working textual DJ decks."
—Erik Davis, Bookforum