This book constitutes the proceedings of the 18th International Conference, CISIS 2025, held in Salamanca, Spain, during October 16-17, 2025.
The 17 full papers included in this volume were carefully reviewed and selected from 36 submissions. The papers cover the following topical sections: Malware & Intrusion Detection; Cryptography & Blockchain Security; and AI Safety, Privacy & Trustworthy Systems.The papers also include the special session: Artificial Intelligence for Protecting the Internet of Things.